9,9-dimethyl-10-amino-alkylacridans



United States Patent U.S. Cl. 260279 3 Claims ABSTRACT OF THE DISCLOSURE 10 {3 [5 chloro 2 (p-chlorophen0Xy)anilino] propyl}-9,9-dimethylacridan and the corresponding N- lower alkyl compounds have pharmacological activity; e.g., analgesic activity.

CROSS-REFERENCE This is a division of Serial No. 535,684 filed Mar. 21, 1966, now US. Patent No. 3,452,021.

DESCRIPTION OF INVENTION This invention pertains to -{3-[5-chloro-2-(pchlorophenoxy)anilino]propyl}-9,9-dimethylacridan of the formula:

CH3 CH I CHzCHzCHzNH 3,498,987. Patented Mar. 3, 1970 to the N-lower alkyl derivatives thereof, and to the pharmaceutically acceptable non-toxic salts thereof.

The manner and process of making and using this invention is described in US. Patent No. 3,452,021, issued June 24, 1969, the disclosure of which is herein incorporated by reference.

We claim:

1. A compound selected from the group consisting of 10 {3 [5 chloro 2 (pchlorophenoxy)anilino] propyl} 9,9 dimethylacridan and 10-{3-[5-ch10r0-2-(pchlorophenoxy) N lower alkylanilino}-9,9 dimethylacridans.

2. The compound according to claim 1 which is 10-{3- [5 chloro 2 (p-chlorophenoxy)anilino]propyl}-9,9- dimethylacridan.

3. The pharmaceutically acceptable nontoxic acid addition salts of a compound according to claim 1.

References Cited UNITED STATES PATENTS 3,284,454 12/1966 Haring et a1. 260-279 DONALD G. DAUS, Primary Examiner US. Cl. X.R. 424-257 @3 3?" UNITED STATES PATENT OFFICE CERTIFICATE OF CORRECTION Patent No. 3,493,9 7 Dated March 3 1970 Inv nmfl Mex Mp-iqp'lq and Angplo Storni It is certified that error appears in the above-identified patenr and that said Letters Patent are hereby corrected as shown below:

In column 2, line 17, "claim 1" should be claim 2 SIGNED KND SEALED JUL 1 41970 Attest:

Edward M. Fletcher, In mun E. somJYnmR, JI- Attesting Officer t- 

